Pregnenolone can neutralize the effects of Cannabis

A group of French researchers have found that the brain has a natural defense against the "high" effects of marijuana. Reported by Agence France-Presse (AFP), the researchers conducted an investigation using rats.

Illustration of the effects of Cannabis. (Picture from: MedicalDaily)

As a result, they discovered a natural hormone called pregnenolone seems to neutralize the "high" effect of marijuana. A study published in Science journal explained that pregnenolone was initially regarded as a "pioneer of all active steroid hormones."

However in this study, "pregnenolone blocking behavior and the effects of tetrahydrocannabinol (THC, the psychoactive ingredient contained in marijuana)." This suggests that the research "can bring a new approach to treating poisoning and addiction to cannabis, as well as allowing researchers to separate the properties of cannabis while blocking behavior and somatic effects."

However, Pier Vincenzo Piazza of the Institute of Health and Medical Research of France told the AFP that the mice in the study had high (stoned). They were given 3 to 10 times the amount of marijuana from the normal condition. In the pregnenolone discovery that may inhibit high effect in mice, the researchers began experimenting on human cell lines. Obtained the same results, and the next step is to conduct full-scale clinical trials. *** [EKA | FROM VARIOUS SOURCES | MEDICAL DAILY]

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