Some say as good as any drug, that the sick people's mindset and suggestion are not positive towards their health recovery, drink drugs will not cure. Is it true that the suggestion had that much power?
Biopsychology and Physiology lecturer, Tauhid Nur Azhar confirmed it. According to him, the suggestion plays a very important role in the people's healing process. "Suggestibility factor will encourage the process of self healing is performed by the HPA (hypothalamic, pituitary, adrenal) axis. Where the axis as Hans Selye's theory of stress with the general adaptation concept will make levels of the important hormones fluctuate," said Tauhid explained.
According to him, in psychoneuroimmunology theory that as high as the stress hormones such as ACTH and cortisol will give pressure on the immune system. The research suggests that cortisol can inhibit the differentiation and maturation of lymphocytes, reducing the effectiveness of the oxidative burst in macrophages, as well as reducing the activity of antigen-cells and presenting MHC class II.
"The constructive thinking concept to face of sick conditions will balance the endocrine or hormonal response. Dopamine, serotonin, and endorphins hormone will reduce the cortisol impact as well as to encourage or stimulate the immune system. Sense of joy and optimism turned out to strengthen the immune system," said Tauhid further.
According to him, the pray power could activate the endorphins, serotonin, and dopamine which then activates cellular and humoral immunity and reduce the free radical formation reactions and activate natural antioxidative system.
So, which one is more powerful, suggestion or drugs?
"Basically, the number one is the faith through praying activities will cause a sense of calm transform into a positive suggestion because we believe there is a resting-place and place for help. This will activate the limbic system, specifically the hippocampus, prefrontal cortex, and also nucleus accumbens as the reward center, or pleasure center," said Tauhid.
MRI scan results on spiritual leaders who are in the solemn state show the activation patterns in the brain area. Followed by the alpha-theta brain waves modulation which stimulate the body to relax, repair themselves, and activate the immune system, also optimize metabolism.
On this condition, the healing process become more optimal. Of course, this condition must be supported by the availability of tissue repair material, the drug's active ingredient that could help metabolism, repair process, and launched biochemical reactions such as enzymatic and hormonal reactions. Thus, the psychological condition and availability of substances in the drugs must be in comprehensive, integrated, and complementary synergy.
How do drugs work in Our body?
Type, substance, and function of drugs, as well as pthe entry process and interact with a variety of body tissues can be studied in pharmacology. SSo to be able to know the drug reaction in Our body, we have to understand the basics of pharmacology that have sub disciplines such as pharmacokinetics, pharmacodynamics, pharmacognosy, and also pharmacogenetic or pharmacogenomic.
"To ensure a therapeutic effect, the drug must be the correct type, eg for fever were given acetaminophen or paracetamol. Then have the right dosage, as well as given at the correct time. Speed of drugs into the body and then absorbed by the body as well as the therapeutic effects can be studied in pharmacokinetics. Where the factors that influence it, among others, the degree of solubility, solvent type, concentration or molarity of drug substance, enzymatic reactions and also various the body biochemical reactions such as which occur in the oral cavity by saliva and in the stomach by HCl acid," said Tauhid explained.
Most of the drugs substances that enter will be absorbed in the small intestine and enter the vasculature system of hepatic portal that will take to be processed in the liver. Furthermore, after the enzymatic and detoxification reactions through a series of oxidation reactions, drug molecules to the systemic circulation in the target organ. Pharmacodynamics of the drug in the target organ or target receptor is highly dependent on the receptivity or the ability of the drug molecules to utilize the pathways into intracellular through specific or non-specific channels, such as Ca Channel or Calcium Channel.
"From there then the drug will work to improve the cellular or physiological functions in other cases improve metabolic function, hormonal, and enzymatic as well as substitution and complementation of elements of the body needs," said Tauhid.
Therefore, according to him, that the drug is not on target will harm the human body itself. Reactions that commonly occur are: first, an incurable disease or cell or organ function did not improve. Second, drugs that are not needed by the body is actually become a burden to the detoxification process in the liver and increase the metabolite to be excreted by the kidneys.
Similar delivered by Dr R Hendi who works at Bina Sehat Hospital. According to him, the proper diagnosis of the patient plays an important role. "To provide the proper medication, proper diagnosis should also. Not all diseases that occur in every person healed by the same medicine. Should be learned properly how each patient's condition, whether allergic to certain substances, ages, and weights should also be considered. Especially if giving drugs to children," he said.
According Hendi, fault diagnosis and drug delivery will be fatal that could lead to one's death. He also stressed that not all diseases can be cured by giving antibiotics. "Antibiotics may seem fast to provide relief, but due to the long term will make the bacteria become stronger. Especially if the patient is taking the medication until the patient is not discharged. Therefore, antibiotics are not the ultimate solution to every disease," he said. *** [EKA | FROM VARIOUS SOURCES | FEBY SYARIFAH | PIKIRAN RAKYAT 12092013]
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